Precisely what is NMN?
NMN is brief for nicotinamide mononucleotide, a naturally sourced molecule present in all species. For the molecular level, this is a ribonucleotide, a simple structural unit from the nucleic acid RNA. It has a nicotinamide group, a ribose, and a phosphate group.
NMN is a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that may be attractive slowing some areas of aging. NAD+ serves many critical functions within our cells, such as electron transport, cell signaling, and DNA repair.
Accumulating evidence suggests that as we grow older, our amounts of NAD+ decline, increasing our risk of age-related diseases.
This is when the NAD+ precursor NMN comes in. Some researchers think that if we can restore that lost NAD+, we will not just decelerate aging but also delay various age-related diseases. Whether or not restoring NAD+ metabolism in humans will slow down aging or support healthy longevity remains an unanswered question, although the animal information is promising.
What foods contain NMN?
NMN is found naturally in foods for example avocado, broccoli, cabbage, cucumber, and edamame. Here is how much NMN is found in some common foods.
While these kinds of foods are an excellent source of nutrition, dietary NMN supplements are also available. These supplements typically appear in doses which can be between 100 – 500 mg, although an optimal dose has not determined in people.
Fasting and caloric restriction also appear to increase NAD+ levels and raise the activity of sirtuins, aka the longevity genes. It is strongly recommended that their activity depends on the existence of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and yes it appears to be slow aging.
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